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Monday, September 7, 2015

Bacterial vaccine

Live attenuated
BCG

Killed/inactivated
Pertussive
Cholera
Thyphoid

Sub-unit
N.menigitidis
H.influenzae
S.pneumonia

Toxoid
Diphtheria
Tetanus

Chromaffin cells

CHROMAFFIN CELLS
These cells are derived embryologically from the neuro-ectoderm (neural crest).

During development, chromaffin cells are widely scattered within the embryo.
But in the adult, these can only be found in the adrenal medulla which is innervated by pre-ganglionic fibres from the thoracic spinal cord via the splanchnic nerves.

These fibres synapse directly with the chromaffin cells which are homologous to sympathetic post-ganglionic neurons and can generate action potential * ·

             Sympathetic pre-ganglionic fibres are myelinated while post-ganglionic fibres are non-myelinated. All pre-ganglionic fibres secrete acetylcholine *

Saturday, July 25, 2015

Pseudomonas aeruginosa

Gram negative bacilli
Non fermentative
Cause
Nosocomial UTI
Nosocomial RTI
Opportunistic wound infection
Bacteraemia
Septicaemia

Wednesday, April 1, 2015

Hb Bart syndrome

It is the most severe form of alpha thalassaemia. Caused by mutation or deletion of all 4 alpha globin alleles (copies of the alpha globin genes) causing a lack of production of alpha hemoglobin.