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Wednesday, July 3, 2013

Contraceptive patch

Contraceptive patch

A contraceptive patch is a transdermal patch applied to the skin that releases synthetic estrogen and progestogen hormone. They have been shown to be as effective as combined oral contraceptive pills with perfect use ( failure rate approximately 1% first year). The currently available patches are Ortho Evra and Evra. The patch can be applied to upper outer arm, buttocks, abdomen or thigh. Seven days later, the patch is removed and another new patch is applied. After using 3 patch (3 weeks), there is a patch free week.
        The patch should be applied to the skin that is clean, dry and intact. Lotions, powder or makeup must be avoided around the area where the patch is applied. The patch works primarily by prevention of ovulation. A secondary mechanism of action is inhibition of sperm penetration by changes in cervical mucous. There may also be prevention of implantation.
        A 20cm2 Ortho Evra patch contains 750mcg ethinyl estradiol and 6000mcg norelgestromin. Twenty microgram of ethinyl estradiol and 150mcg of norelgestromin per day are relased into the circulation. These patches have similar benefits to the combined oral contraceptive pills. Risks are also similar.

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